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. 2021 Aug 14;16:5513–5529. doi: 10.2147/IJN.S322688

Figure 1.

Figure 1

Structure of oxoplatins O1 and O2, dual naproxen platinum(IV) complexes 1 and 2, the preparation of nanoparticles 1-NPs and 2-NPs, and their likely antitumor mechanism.

Abbreviations: NPs, nanoparticles; BSA, bovine serum albumin; COX-2, cyclooxygenase-2; MMP-9, metalloproteinase-9; iNOS, inducible nitric oxide synthase.