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. 2021 Aug 5;12:700892. doi: 10.3389/fmicb.2021.700892

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Copyright © 2021 Li, Zhang, Su, Tian, Mei, Zhang, Wang, Li and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cytotoxic activity of TIGIT⁺ T cells in spleen after T. gondii infection. (A) Dynamic changes in TIGIT⁺CD4⁺ T cell cytotoxicity in the spleen of mice chronically infected with T. gondii. (B) Dynamic changes of TIGIT⁺CD8⁺ T cell cytotoxicity in the spleen of mice chronically infected with T. gondii. The results are representative of three independent experiments with five mice in each group per experiment, with data denoting means ± SDs. *p < 0.05, **p < 0.01, and ***p < 0.001 (compared to the control).