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. 2021 Aug 5;9:673618. doi: 10.3389/fcell.2021.673618

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Copyright © 2021 Mao, Gu, Sui, Shen, Han, Wang, Xi, Zhuang, Meng and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Quantification of relative gene expressions of DRP1, FIS1, MFF, MFN1, MFN2, OPA1, PINK1, and PARKIN by real-time PCR. (B) Levels of DRP1, p-DRP1(ser616), p-DRP1(ser637), FIS1, MFF, MFN1, MFN2, OPA1, and GAPDH by Western blot. (C) Quantification of DRP1, p-DRP1(ser616), p-DRP1(ser637), and DRP1/p-DRP1 ratio. (D) Quantification of FIS1, MFF, MFN1, MFN2, and OPA1. C, control, patients with benign disease; NC, patients of non-cachexia; CAC, cancer patients with cachexia. *p < 0.05. Data are displayed as mean ± standard deviation.