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. 2021 Aug 5;9:669145. doi: 10.3389/fcell.2021.669145

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Copyright © 2021 Xu, Xu, Deng, Li, Mu, Qi, Shen, Wang, Wen, Zhao, Weng and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The clinical significance of ZC3H13 in HCC. ZC3H13 are downregulated in HCC samples based on the TCGA dataset (A) and cell lines (B), and lower ZC3H13 expression level was significantly correlated with improved prognosis (C). Correlation analysis of prognosis-related genes with infiltrating CD4 + T cells (D), CD8 + T cells (E), dendritic cells (F), macrophages (G), and neutrophils (H) using TIMER. The association between the expression levels of ZC3H13 with CD274 (I), HAVCR2 (J), IDO1 (K), and PDCD1LG2 (L) using TIMER.