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. 2021 Apr 21;88(3):291–316. doi: 10.1177/00243639211005121

Table 8.

Estimated Economic Impact of Combined Oral Contraceptives due to Increased Incidence of Ulcerative Colitis.

Women of reproductive age Number on the pill Incidence
61,000,000 9,699,000 0.000122
Estimated women on the pill at risk 1,183
Adjusted estimate 1,444 1.22 (0.74–2.07) Low RR (95 percent CI)
Adjusted estimate 1,870 1.58 (0.71–3.52) High RR (95 percent CI)
Excess cases 260 Low RR
Excess cases 686 High RR
Annual cost per patient with ulcerative colitis US$12,900
Estimated annual costs US$3,358,143 Low RR
Estimated annual costs US$8,853,286 High RR

Note: CI = confidence interval; RR = relative risk.