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. 2021 Aug 5;11:694395. doi: 10.3389/fcimb.2021.694395

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Copyright © 2021 Ji, Sun, Fu, She, Liu, He, Ai, Li and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The growth of mice in the control group, mice in the NA group and mice in the NEC group. Mice in the NEC group were smaller than those in the control group and NA group. (B) Body weight changes of newborn mice in the three groups. Numbers of samples: Con (n=10), NEC (n=10), and NA (n=10). Statistics: two-way ANOVA multiple comparisons method. (C) Survival curves of newborn mice in three groups. The survival rate was estimated during modeling, and the results are shown as a Kaplan–Meier plot, with 54 mice in each group at the beginning. Statistics: log-rank (Mantel-Cox) test (P < 0.05). Control – normal control, NEC – necrotizing enterocolitis, NA – necrotizing enterocolitis+AI-2.