Table 1.
Characteristics of 15 Patients With Sclerotic-Type Chronic Graft-vs-Host Disease (cGVHD)
Patient No./Sex/Age, y | Primary Diagnosis | Time From Stem Cell Transplantation, moa | cGVHD |
|
---|---|---|---|---|
Onset | Other Organ Involvement at the Time of Evaluation | |||
1/F/40 | Non-Hodgkin lymphoma | 33 | Progressive | Ophthalmologic, GI, hepatic, J/F, oral, and vulvovaginal |
2/F/39 | AML | 16 | Quiescent | Ophthalmologic, GI, hepatic, J/F, oral, pulmonary, and vulvovaginal |
3/M/40 | AML | 53 | Progressive | Ophthalmologic, J/F, oral, and pulmonary |
4/F/42 | CML | 39 | De novo | Ophthalmologic, J/F, oral, and pulmonary |
5/M/56 | MM | 37 | De novo | J/F and oral |
6/M/62 | MM | 105 | Progressive | J/F and oral |
7/F/38 | AML | 29 | Progressive | Ophthalmologic, hepatic, J/F, oral, pulmonary, and vulvovaginal |
8/M/57 | Myelodysplastic syndrome | 45 | Progressive | Ophthalmologic, J/F, and oral |
9/M/51 | CML | 21 | De novo | Hepatic, J/F, and oral |
10/M/45 | T-cell lymphoblastic leukemia | 26 | De novo | Ophthalmologic, hepatic, J/F, and oral |
11/M/40 | AML | 67 | De novo | Ophthalmologic, J/F, and oral |
12/M/32 | T-cell lymphoma | 22 | De novo | GI, hepatic, J/F, and oral |
13/M/57 | Chronic lymphocytic leukemia | 52 | Progressive | J/F |
14/F/20 | Acute lymphoblastic leukemia | 26 | De novo | Ophthalmologic, GI, hepatic, J/F, oral, and pulmonary |
15/M/60 | Myeloid metaplasia with myelofibrosis | 21 | Progressive | Ophthalmologic, hepatic, and oral |
Abbreviations: AML, acute myelogenous lymphoma; CML, chronic myelogenous leukemia; GI, gastrointestinal; J/F, joint and fascia (physiatry assessment); MM, multiple myeloma.
Interval between stem cell transplantation and evaluation at the National Institutes of Health.