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Differences between low-grade tumors and high-grade leiomyosarcomas
| Low-grade tumors (19) | High-grade leiomyosarcomas (31) | |
|---|---|---|
|
| ||
| Mean age (y) | 45 | 52 |
| Nuclear atypia | Mild | Marked |
| Coagulative necrosis | Mixed with hyaline areas | Present, without hyaline areas |
| Mitoses (per 10HPF) | 5 | 13 |
| First site of metastases | ||
| Pelvis | 79% | 19% |
| Lung | 16% | 70% |
| Metastases in organs | 21% | 81% |
| Mean time to recurrence (mo) | 52 | 19 |
| Patients who died of disease | 3 (16%) | 27 (87%)* |
P value <0.0001 (Fisher exact test).
