Table 2.
Panel A: Associations between max VO2 and domain-specific cognitive performance | 95% Confidence Interval | |||
---|---|---|---|---|
Estfc | Lower | Upper | B-H p d | |
Executive functiond | .324 | .064 | .585 | .025 |
Episodic memorye | .391 | .129 | .653 | .008 |
Visuospatialf | .570 | .238 | .901 | .005 |
Attentiong | .081 | −.241 | .403 | .623 |
Languageh | .243 | −.164 | .651 | .302 |
Panel B: Associations between max VO2 and structural magnetic resonance imaging derived brain volumese | 95% Confidence Interval | |||
Estc | lower | upper | B-H p d | |
Thalamus | .722 | .430 | 1.015 | .004 |
Pallidum | .635 | .354 | .916 | .004 |
Caudate nucleus | .155 | −.260 | .571 | .464 |
Putamen | −.248 | −.585 | .088 | .395 |
Dorsolateral prefrontal cortex | .095 | −.326 | .516 | .813 |
Nucleus accumbens | .119 | −.242 | .479 | .813 |
Anterior cingulate | −.113 | −.409 | .183 | .813 |
Hippocampus | −.081 | −.511 | .348 | .813 |
Cerebellum | .024 | −.245 | .294 | .859 |
Bolded estimates denote p < .05
maximum VO2 was estimated by the Ebbling Single State Submaximal Treadmill Walking Test and z-score standardized (mean = 0; standard deviation=1) based on the sample mean and standard deviation.
all cognitive outcomes were z-score standardized (mean = 0; standard deviation =1).
parameter estimates were adjusted for covariates.
p value represents the Benjamini-Hochberg adjusted p value to correct for multiple comparisons.
brain volumes were derived from structural magnetic resonance imaging, were corrected for intracranial volume and were z-score standardized using the sample mean and standard deviation.