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. Author manuscript; available in PMC: 2021 Aug 19.
Published in final edited form as: Parkinsonism Relat Disord. 2021 Mar 29;86:19–26. doi: 10.1016/j.parkreldis.2021.03.019

Table 2.

Associations between maximum VO2a and domain-specific cognitive performanceb are presented in panel A while association between maximum VO2 and structural magnetic resonance imaging derived brain volumes are presented in panel B (N = 33).

Panel A: Associations between max VO2 and domain-specific cognitive performance 95% Confidence Interval
Estfc Lower Upper B-H p d
 Executive functiond .324 .064 .585 .025
 Episodic memorye .391 .129 .653 .008
 Visuospatialf .570 .238 .901 .005
 Attentiong .081 −.241 .403 .623
 Languageh .243 −.164 .651 .302
Panel B: Associations between max VO2 and structural magnetic resonance imaging derived brain volumese 95% Confidence Interval
Estc lower upper B-H p d
 Thalamus .722 .430 1.015 .004
 Pallidum .635 .354 .916 .004
 Caudate nucleus .155 −.260 .571 .464
 Putamen −.248 −.585 .088 .395
 Dorsolateral prefrontal cortex .095 −.326 .516 .813
 Nucleus accumbens .119 −.242 .479 .813
 Anterior cingulate −.113 −.409 .183 .813
 Hippocampus −.081 −.511 .348 .813
 Cerebellum .024 −.245 .294 .859

Bolded estimates denote p < .05

a

maximum VO2 was estimated by the Ebbling Single State Submaximal Treadmill Walking Test and z-score standardized (mean = 0; standard deviation=1) based on the sample mean and standard deviation.

b

all cognitive outcomes were z-score standardized (mean = 0; standard deviation =1).

c

parameter estimates were adjusted for covariates.

d

p value represents the Benjamini-Hochberg adjusted p value to correct for multiple comparisons.

e

brain volumes were derived from structural magnetic resonance imaging, were corrected for intracranial volume and were z-score standardized using the sample mean and standard deviation.