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Sources of Incidentally Identified VUS Reporting
| Sources of Incidentally Identified VUS Reporting |
|---|
| Referring physician requests expanded variant list |
| Interpretation of variant pathogenicity evolves over time |
| Discrepancies in interpretation between genetic testing companies/laboratories |
| VUS identified on gene panel sent for incorrect clinical indication |
| Non-CLIA-approved genetic testing, direct to consumer/consumer-initiated panels |
| Research-based genetic testing |
