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. Author manuscript; available in PMC: 2021 Aug 19.
Published in final edited form as: J Invest Dermatol. 2019 Aug 15;140(2):435–444.e4. doi: 10.1016/j.jid.2019.06.146

Figure 2. Il17ra L-SNA suppresses mRNA expression of inflammatory and proliferation markers and increases mRNA expression of genes promoting cell differentiation.

Figure 2.

qRT-PCR of immune (a-f) proliferation (g) and differentiation (h, i) biomarkers associated with psoriasis. Expression of mouse 60S acidic ribosomal protein P0 and glyceraldehyde-3-phosphate dehydrogenase were averaged as a normalization control. Skin without imiquimod (IMQ) treatment was set as the comparator (no IMQ =1.0). Values are expressed as mean + standard error of the mean. *P < 0.05, **P < 0.01, ***P < 0.001. IL-17RA, IL-17A receptor; IMQ, imiquimod; qRT-PCR, quantitative real-time reverse transcriptase–PCR; Scr L-SNA, scrambled liposomal spherical nucleic acid.