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. 2021 Aug 5;12:629276. doi: 10.3389/fphys.2021.629276

FIGURE 3.

FIGURE 3

Effect of capsaicin on Sox5 in guinea pig and neuronal cells. (A) Expression level of SOX5 after capsaicin treatment in guinea pigs. Data are mean ± SEM; two-tailed t-test was used for statistical analysis. (B) mRNA expression level of SOX5 in guinea pigs after capsaicin treatment. Data are mean ± SEM; two-tailed t-test was used for statistical analysis. (C) Expression level of SOX5 after capsaicin treatment in neuronal cells. Data are mean ± SEM; two-tailed t-test was used for statistical analysis. (D) mRNA expression level of SOX5 in neuronal cells after capsaicin treatment. Data are mean ± SEM; two-tailed t-test was used for statistical analysis. (E) SOX5 level, as determined using immunofluorescence, and SOX5-positive staining in trachea and lung tissues of guinea pigs. Data are mean ± SEM; two-tailed t-test was used for statistical analysis. (F) Immunostaining analysis showing that capsaicin upregulated the expression of SOX5 in neuronal cells. Scale bars represent 100 μm. **P < 0.01; n = 7.