Table 3:
Spearman rho correlation coefficient for markers of eGC breakdown, endothelial activation and disease severity
| Ang-2 | Syndecan-1 | GAG | Hemoglobin | Platelet | HRP2 | ||
|---|---|---|---|---|---|---|---|
| Ang-2 | MSM | 0.379 | 0.192 | −0.317 | −0.405 | 0.497 ** | |
| SM | 0.653 ** | 0.541 ** | −0.372 | −0.338 | −0.007 | ||
| All | 0.520 ** | 0.410 ** | −0.378 ** | −0.427 ** | 0.254 | ||
| Syn-1 | MSM | 0.379 | 0.247 | −0.353 | −0.365 | 0.424 ** | |
| SM | 0.653 ** | 0.395 | −0.410 ** | −0.242 | 0.167 | ||
| All | 0.520 ** | 0.341 ** | −0.403 ** | −0.355 ** | 0.289 ** | ||
| GAG | MSM | 0.192 | 0.247 | −0.300 | −0.146 | 0.089 | |
| SM | 0.541 ** | 0.395 | −0.452 ** | −0.410** | 0.116 | ||
| All | 0.410 ** | 0.341 ** | −0.441 ** | −0.327 ** | 0.107 | ||
| Hb | MSM | −0.317 | −0.353 | −0.300 | 0.486 ** | −0.515 ** | |
| SM | −0.372 | −0.410 ** | −0.452 ** | 0.239 | −0.044 | ||
| All | −0.378 ** | −0.403 ** | −0.441 ** | 0.440 ** | −0.330 ** | ||
| Platelet | MSM | −0.405 | −0.365 | −0.146 | 0.486 ** | −0.595 ** | |
| SM | −0.338 | −0.242 | −0.410** | 0.239 | −0.399 | ||
| All | −0.427 ** | −0.355 ** | −0.327 ** | 0.440 ** | −0.502 ** | ||
| HRP2 | MSM | 0.497 ** | 0.424 ** | 0.089 | −0.515 ** | −0.595 ** | |
| SM | −0.007 | 0.167 | 0.116 | −0.044 | −0.399 | ||
| All | 0.254 | 0.289 ** | 0.107 | −0.330 ** | −0.502 ** | ||
Spearman rho correlation coefficients. Bold face indicates significant values (**p ≤0.01)
Bonferroni method was used to adjust for multiple comparisons and the new alpha level was determined to be 0.01.
MSM: moderately severe malaria; SM: severe malaria; “All” refers to the combined MSM and SM groups