Table 4.
Glycocalyx Imaging Results, Axillaa
| Parameter | Healthy Control (n=53) |
Moderately Severe Malaria (n=38) |
Severe Malaria (n=37) |
P valueb |
|---|---|---|---|---|
| PBR 5-25 (μm) | 1.86 (0.63-3.09) | 2.17 (1.35-3.58) | 1.94 (1.39-3.54) | 0.094 |
| PBR 5-9 (μm) | 1.18 (0.45-1.79) | 1.20 (0.75-2.02) | 1.20 (0.54-1.54) | 0.460 |
| PBR 10-19 (μm) | 2.10 (0.70-3.83) | 2.29 (1.46-3.78) | 2.17 (1.18-4.08) | 0.169 |
| PBR 20-25 (μm) | 2.17 (0.71-3.57) | 2.55 (1.48-4.05)* | 2.32 (1.46-4.31) | 0.038 |
| RBC filling (%) | 71.7 (38.6-96.2) | 64.5 (27.5-86.0) | 68.9 (34.5-92.4) | 0.131 |
| Density (μm/mm2) | 247 (79-816) | 353 (86-869) | 349 (110-739) | 0.061 |
a
Median (range), except when indicated otherwise
b
ANOVA or Kruskal-Wallis test for comparison of HC, MSM and SM groups
*
p<0.05 between group comparison vs. HC