Table 1.
Baseline characteristics of study population by FBG levels and stroke risk: Cohort Changshu
| Characteristic | Total | Quartile of FBG levels (mmol/L) | P value | |||
| n=16 113 | Q1 (<4.87) n=4097 |
Q2 (4.87–5.24) n=4027 |
Q3 (5.24–5.77) n=3979 |
Q4 (>5.77) n=4010 |
||
| Age, years | 55.7 (46.3, 64.4) | 48.6 (41.4, 59.1) | 53.8 (44.8,62.84) | 57.8 (48.6, 65.9) | 60.0 (51.4, 67.2) | <0.001 |
| Men (%) | 40.9 | 42.1 | 39.4 | 40.2 | 42.1 | 0.002 |
| Premenopausal in women (%) | 37.5 | 55.3 | 42.3 | 29.7 | 22.3 | <0.001 |
| Follow-up time, years | 5.53 (5.49, 5.56) | 5.52 (5.49, 5.54) | 5.52 (5.49, 5.55) | 5.53 (5.50, 5.57) | 5.55 (5.50, 5.58) | <0.001 |
| BMI (kg/m)* | 23.3 (21.2, 25.7) | 22.6 (20.6, 24.9) | 23.0 (21.0, 25.3) | 23.6 (21.5, 25.9) | 24.2 (22.0, 26.5) | <0.001 |
| Current smoking (%) | 23.6 | 26.9 | 23.5 | 21.9 | 21.9 | <0.001 |
| Family history of stroke (%) | 5.8 | 3.8 | 5.4 | 6.5 | 7.6 | <0.001 |
| Hypertension (%) | 22.8 | 13.9 | 18.6 | 24.9 | 34.0 | <0.001 |
| Fasting blood glucose, mmol/L | 5.24 (4.87. 5.77) | 4.66 (4.47, 4.77) | 5.06 (4.97, 5.15) | 5.47 (5.34, 5.60) | 6.37 (6.01, 7.20) | <0.001 |
| impaired fasting glucose (%) | 8.6 | — | — | — | 34.7 | <0.001 |
| Diabetes (%) | 8.8 | 0.6 | 0.7 | 1.0 | 33.3 | <0.001 |
| TC, mmol/L | 4.70 (4.13, 5.36) | 4.48 (3.95, 5.04) | 4.62 (4.08, 5.23) | 4.79 (4.22, 5.44) | 4.99 (4.36, 5.70) | <0.001 |
| TG, mmol/L | 1.32 (0.96, 1.90) | 1.20 (0.88, 1.68) | 1.26 (0.93, 1.78) | 1.33 (0.97, 1.91) | 1.52 (1.08, 2.30) | <0.001 |
| HDL-C, mmol/L | 1.38 (1.14, 1.66) | 1.36 (1.14, 1.62) | 1.37 (1.14, 1.64) | 1.40 (1.15, 2.68) | 1.38 (1.14, 1.69) | <0.001 |
| LDL-C, mmol/L | 2.57 (1.92, 3.27) | 2.64 (2.03, 3.34) | 2.62 (1.97, 3.30) | 2.55 (1.89, 3.26) | 2.47 (1.79, 3.17) | <0.001 |
| eGFR (mL/min/1.73 m²) | 95.59 (84.39, 105.42) | 100.88 (89.80, 110.06) | 96.744 (86.38, 106.50) | 93.60 (83.12, 102.95) | 91.65 (79.13, 101.17) | <0.001 |
| Use of statins (%) | 0.4 | 0.1 | 0.3 | 0.3 | 0.7 | <0.001 |
*P values were determined by χ2 tests for categorical and Kruskal-Wallis tests for continuous variables.
BMI, body mass index; eGFR, estimated glomerular filtration rate; FBG, fasting blood glucose; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Q, quartile; TC, total cholesterol; TG, triglyceride.