Table 2.

HRs (95% CI) for incident stroke by FBG quartiles

		Quartile of FBG levels				P trend
		Q1	Q2	Q3	Q4
		HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)
Total stroke	Cases/N	57/4097	89/4027	110/3979	161/4010
	Model 1	1 (Ref.)	1.60 (1.15 to 2.22)	2.00 (1.45 to 2.75)	2.92 (2.16 to 3.94)	<0.001
	Model 2	1 (Ref.)	1.21 (0.87 to 1.69)	1.17 (0.85 to 1.62)	1.46 (1.07 to 1.98)	0.018
	Model 3	1 (Ref.)	1.19 (0.86 to 1.63)	1.16 (0.86 to 1.62)	1.44 (1.07 to 1.94)	0.021
Ischaemic stroke	Cases/N	42/4097	69/4027	83/3979	129/4010
	Model 1	1 (Ref.)	1.68 (1.15 to 2.47)	2.05 (1.41 to 2.96)	3.17 (2.24 to 4.49)	<0.001
	Model 2	1 (Ref.)	1.27 (0.87 to 1.87)	1.19 (0.82 to 1.73)	1.58 (1.11 to 2.25)	0.013
	Model 3	1 (Ref.)	1.25 (0.91 to 1.86)	1.17 (0.81 to 1.70)	1.57 (1.11 to 2.21)	0.016
Non-ischaemic stroke	Cases/N	15/4097	20/4027	27/3979	32/4010
	Model 1	1 (Ref.)	1.36 (0.70 to 2.66)	1.86 (0.99 to 3.50)	2.20 (1.19 to 4.07)	0.006
	Model 2	1 (Ref.)	1.04 (0.53 to 2.04)	1.13 (0.60 to 2.14)	1.11 (0.59 to 2.07)	0.713
	Model 3	1 (Ref.)	1.10 (0.57 to 2.14)	1.12 (0.64 to 2.24)	1.07 (0.57 to 1.99)	0.844

Model 1: unadjusted model; model 2: adjusted for age, sex and BMI; model 3: further adjusted for HDL-C, TC, TG, LDL-C, eGFR, hypertension, smoking status, use of statins and family history of stroke.

eGFR, estimated glomerular filtration rate; FBG, fasting blood glucose; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglyceride.