Table 3.
HRs (95% CI) for incident stroke by clinical classifications of FBG levels
| Model 1 | Model 2 | Model 3 | |||
| ADA definition | <5.6 mmol/L | Cases/N | 220/11079 | ||
| HR (95% CI) | 1 (Ref.) | 1 (Ref.) | 1 (Ref.) | ||
| 5.6–6.9 mmol/L | Cases/N | 136/3869 | |||
| HR (95% CI) | 1.78 (1.43 to 2.20) | 1.16 (0.94 to 1.44) | 1.17 (0.93 to 1.42) | ||
| ≥7.0 mmol/L | Cases/N | 61/1165 | |||
| HR (95% CI) | 2.69 (2.02 to 3.57) | 1.72 (1.29 to 2.28) | 1.68 (1.24 to 2.27) | ||
| P trend | <0.001 | 0.001 | 0.001 | ||
| WHO definition | <6.1 mmol/L | Cases/N | 301/13422 | ||
| HR (95% CI) | 1 (Ref.) | 1 (Ref.) | 1 (Ref.) | ||
| 6.1–6.9 mmol/L | Cases/N | 55/1526 | |||
| HR (95% CI) | 1.61 (1.21 to 2.15) | 1.08 (0.81 to 1.45) | 1.11 (0.83 to 1.47) | ||
| ≥7.0 mmol/L | Cases/N | 61/1165 | |||
| HR (95% CI) | 2.38 (1.81 to 3.03) | 1.64 (1.24 to 2.17) | 1.62 (1.21 to 2.13) | ||
| P trend | <0.001 | 0.001 | 0.002 | ||
Model 1: unadjusted model; model 2: adjusted for age, sex and BMI; model 3: further adjusted for HDL-C, TC, TG, LDL-C, eGFR, hypertension, smoking status, use of statins and family history of stroke.
ADA, American Diabetes Association; eGFR, estimated glomerular filtration rate; FBG, fasting blood glucose; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglyceride.