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. 2021 Aug 19;16(8):e0256362. doi: 10.1371/journal.pone.0256362

Table 3. Selected safety profiles of the XEN45 and trabeculectomy groups.

Safety Variable XEN45 (n = 57) Trabeculectomy (n = 57) p-value
Early post-operative; n (%) (within 1 month)    
Wound leak 0 (0.0) 9 (15.8)  0.002*
Subconjunctival hemorrhage 5 (8.8) 0 (0.0)  0.022*
Overdrainage 1 (1.8) 4 (7.0) 0.170*
Choroidal detachment 1 (1.8) 1 (1.8) 1.000*
Hyphema 0 (0.0) 1 (1.8) 0.315*
Late post-operative; n (%) (after 1 month)
Hypotony 1 (1.8) 6 (10.5) 0.041*
Bleb leak 0 (0.0) 3 (6.0) 0.079*
Ptosis 6 (10.5) 2 (3.5) 0.136*
Implant extrusion 3 (5.3) -
Device fracture 1 (1.8) -
Choroidal detachment 0 (0.0) 1 (1.8) 0.315*
Uveitis 1 (1.8) 1 (1.8) 1.000*

*Chi-square test.