TABLE 1.
Combinations of rat strains as orthotopic liver transplantation donor and recipient to model postoperative acute cellular rejection and tolerance
| Donor strain (MHC) | Recipient strain (MHC) | References |
|---|---|---|
| Acute cellular rejection | ||
| LEW (RT1l) | BN (RT1n) | 36-57 |
| DA (RT1av1) | LEW (RT1l) | 58-71 |
| LEW (RT11) | ACI (RT1a) | 72 |
| ACI (RT1a) | LEW (RT1l) | 73,74 |
| Wistar (RT1a/RT1u) | SD (RT1u/RT1b) | 75,76 |
| SD (RT1u/RT1b) | Wistar (RT1a/RT1u) | 51 |
| Tolerance | ||
| BN (RT1n) | LEW (RT1l) | 50 |
| LEW (RT1l) | DA (RT1av1) | 77-80 |
| DA (RT1av1) | PVG (RT1c) | 67 |
| Wistar (RT1a/RT1u) | August (RT1c) | 81 |
ACI, AxC 9935 Irish; BN, Brown Norway; DA, Dark Agouti; LEW, Lewis; MHC, major histocompatibility complex; PVG, piebald virol glaxo; SD, Sprague Dawley.