Table 1.
Demographic and clinical features of the evaluated patients.
Patients | Three hundred forty seven patients | Thirteen patients with VTE |
Gender (female/male) | 87.6%/12.4% | 84.6%/15.4% |
ACR/EULAR 2010 classificative criteria | 100.0% | 100% |
Age, mean ± SD, yr | 66.1 ± 11.3 | 59.3 ± 10.4 |
Disease duration at the first observation, median (range), yr | 5 (28) | 6 (7) |
RF and/or ACPA | 66.1% | 61.5% |
Extra-articular disease | 11.5% | 7.6% |
Smoking habit | 47.8% | 69.2% |
GCs low dose | 73.9% | 76.9% |
GCs high dose | 26.1% | 23.1% |
MTX | 69.7% | 69.2% |
LEF | 17.6% | 23.1% |
SSZ | 9.5% | 0% |
HCQ | 18.1% | 7.7% |
Biologic DMARDs | 47.1% | 69.2% |
TNFi | 35.3% | 35.9% |
Non-TNFi | 11.8% | 33.3% |
Targeted synthetic DMARDs | 2.8% | 0% |
ACPA = anti-citrullinated protein antibody, DMARD = disease-modifying anti-rheumatic drug, GCs = glucocorticoids, HCQ = hydroxychloroquine, LEF = leflunomide, MTX = methotrexate, RF = rheumatoid factor, SSZ = sulfasalazine, TNFis = tumor necrosis factor.