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. 2021 May 12;39(24):2656–2666. doi: 10.1200/JCO.21.00612

FIG 1.

FIG 1.

Change in tumor burden of target lesions, response by subgroup, and response assessment in individual patients. (A) Waterfall plot depicting BOR as assessed by investigator and the best change from baseline in the SOD of the target lesions (per RECIST v1.1 criteria) in the FAS. A change of −100% from baseline is presented for CR assessment that includes lymph node lesions that resolved to < 10 mm. The horizontal dashed line indicates a 30% reduction in the tumor burden in the target lesions. Twelve patients had an increase in the SOD of the target lesions, whereas 50 patients had a decrease in the SOD of the target lesions. Thirty patients (two CR, 22 PR, and six SD) had > 30% reduction in the SOD of the target lesions. Three patients had no post-TIL assessments because of early death. One patient had no post-TIL assessment because of start of new anticancer therapy before day 42.