Table 2.
Subgroup analyses of homocysteine levels and HF.
| Test of SMD = 0 | Heterogeneity | |||||
| Subgroup | Number of studies | SMD (95% CI) | Z | p for Z | I 2 | P for I2 |
| Geographical location | ||||||
| Europe | 8 | 1.062 (0.579, 1.545) | 4.31 | <.001 | 94.5% | <.001 |
| Asia | 2 | 1.127 (0.496, 1.757) | 3.50 | <.001 | 72.8% | .055 |
| Other | 2 | 1.509 (−1.169, 4.187) | 1.10 | .269 | 99.3% | <.001 |
| Sample size | ||||||
| ≥200 | 4 | 0.460 (0.151, 0.770) | 2.92 | .004 | 91.0% | <.001 |
| <200 | 8 | 1.541 (0.786, 2.295) | 4.00 | <.001 | 95.9% | <.001 |
| NOS | ||||||
| 6 | 3 | 1.716 (−0.357, 3.789) | 1.62 | .105 | 98.6% | <.001 |
| 7 | 4 | 0.659 (0.415, 0.903) | 5.28 | <.001 | 61.6% | .050 |
| 8 | 5 | 1.279 (0.528, 2.030) | 3.34 | .001 | 97.0% | <.001 |
CIs = confidence intervals, HF = heart failure, SMDs = standardized mean differences.