FIGURE 2.

NF‐κB species populations resulting from subunit exchange between Rel dimers. (a) Schematic representation of subunit exchange. Proteins are annotated as either “−1” or “−2” variants based on subtle differences in their amino acid length, as demonstrated in the SDS‐PAGE gels at right: 1–p50‐1 RHD, 2–p50‐2 RHD, 3–p65‐1 RHD, 4–p65‐2 RHD. These polypeptide differences encompass regions outside of the dimerisation domains, and therefore do not affect the association properties of the Rel dimers. RHD, Rel homology domain; SDS‐PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis