Table 2.
Effect of naringin, hesperidin, and their combination on liver LPO and antioxidant defense markers in diclofenac-administered rats.
| Parameter | Normal control | Diclofenac | Diclofenac+naringin | Diclofenac+hesperidin | Diclofenac+naringin+hesperidin |
|---|---|---|---|---|---|
| LPO (MDA nmol/g tissue) | 181.75 ± 5.92c | 386.90 ± 14.08a | 174.63 ± 14.83c | 265.03 ± 29.66b | 194.35 ± 19.22c |
| GSH (nmol/100 mg tissue) | 30.50 ± 2.47a | 19.73 ± 1.0c | 20.80 ± 0.79bc | 22.68 ± 0.92bc | 23.73 ± 0.77b |
| GPx (mU/100 mg tissue) | 175.00 ± 4.08a | 46.33 ± 8.34c | 151.17 ± 13.19ab | 140.00 ± 11.90b | 135.00 ± 11.47b |
| SOD (U/g tissue) | 18.43 ± 0.37a | 12.28 ± 0.31c | 15.98 ± 0.75b | 15.65 ± 0.54b | 16.56 ± 0.68b |
Data are expressed as the mean ± SE. Number of animals in each group is six. Means, which share different superscript symbols in the same row, are significantly different at p < 0.05.