Table 3.

The effect of naringin, hesperidin, and their combination on serum TNF-α, IL-17, and IL-4 levels in diclofenac-administered rats.

Serum parameter	Normal control	Diclofenac	Diclofenac+naringin	Diclofenac+hesperidin	Diclofenac+naringin+hesperidin
TNF-α (pg/mL)	33.07 ± 0.51c	154.12 ± 11.63a	102.95 ± 3.44b	88.08 ± 2.37b	91.50 ± 4.67b
IL-17 (pg/mL)	40.05 ± 3.16c	151.48 ± 3.60a	83.30 ± 1.27b	77.60 ± 4.26b	77.60 ± 3.99b
IL-4 (pg/mL)	130.00 ± 3.77a	70.37 ± 3.12d	100.53 ± 0.60c	106.43 ± 2.65c	116.88 ± 2.16b

Data are expressed as the mean ± SE. Number of animals in each group is six. Means, which share different superscript symbols in the same row, are significantly different at p < 0.05.