Table 2.
Clinical data of COVID-19 severe patients according to outcome after ICU care. The survivor group was younger than the non-survivor group and the sex distribution was similar between both groups. In the non-survivor group there was a significantly higher prevalence of hypertension diabetes, cardiovascular diseases and dialysis, higher BMI and, AKI. The other parameters such as days of symptoms, length of ICU stay, pre-hospitalization iRAAS use, in hospital corticosteroid use, SAPS3 and SOFA scores at hospital admission, PO2/FiO2 ratio, white cell blood counts, RCP, creatinine, bilirubin, and lactate were not statistically different between survivor groups and non-survivor groups. Clinical data are expressed as mean ± standard error of mean. BMI=Body max index, RCP=Reactive C-Protein.
| Survivors (n = 30) | Non-survivors (n = 23) | p | |
|---|---|---|---|
| Age | 56.1 ± 2.2. | 64.0 ± 2.4 * | 0.0223 |
| Male sex | 20 (66.7%) | 16 (69.6%) | 0.823 |
| Diabetes | 2 (6.7%) | 8 (34.8%) * | 0.009 |
| Hypertension | 11 (36.6%) | 18 (78.3%) * | 0.006 |
| BMI, kg/m2 | 29.7 ± 1 | 33.7 ± 2 * | 0.0442 |
| CVD | 7 (23.3%) | 12 (52.2%) * | 0.03 |
| iRAAS prehospitalization | 13 (43.3%) | 11 (47.8%) | 0.744 |
| Days of symptoms | 9.7 ± 1 | 10.4 ± 2 | 0.581 |
| Days from symptoms worsening | 2.7 ± 1 | 3.2 ± 1 | 0.333 |
| SAPS3 | 58.3 ± 2.1 | 61.2 ± 2.2 | 0.432 |
| SOFA | 8.2 ± 0.5 | 9.6 ± 0.7 | 0.067 |
| Hospitalization days | 17.5 ± 3 | 13.6 ± 2 | 0.692 |
| In hospital corticoid use | 26 (86.7%) | 21 (91.30%) | 0.597 |
| PaO2/FiO2, ratio | 138.4 ± 20 | 138.3 ± 19 | 0.996 |
| Leukocytes | 10.6 ± 0.8 | 10.9 + 0.95 | 0.805 |
| Neutrophiles | 8.4 + 0.8 | 9.3 + 0.91 | 0.459 |
| Lymphocytes x10/ mm3 | 1.2 + 0.1 | 0.9 + 0.2 | 0.259 |
| Platelets x 103/l | 250 ± 150 | 234 ± 23 | 0.532 |
| Bilirubin (mg/dL) | 0.54 ± 0.1 | 1.14 ± 0.3 | 0.0547 |
| Creatinine (mg/dL) | 1.50 ± 0.2 | 1.65 ± 0.2 | 0.244 |
| Lactate (mg/dL) | 2.19 ± 0.1 | 2.37 ± 0.2 | 0.58 |
| CRP (mg/dL) | 12.55 ± 1.5 | 13.20 ± 1.7 | 0.775 |
| AKI (mg/dL) | 11(36.7%) | 15(65.2%) * | 0.039 |
| Dialysis | 4(13.3%) | 13(56.5%) * | 0.0008 |