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. 2021 Aug 20;142:112067. doi: 10.1016/j.biopha.2021.112067

Table 2.

Clinical data of COVID-19 severe patients according to outcome after ICU care. The survivor group was younger than the non-survivor group and the sex distribution was similar between both groups. In the non-survivor group there was a significantly higher prevalence of hypertension diabetes, cardiovascular diseases and dialysis, higher BMI and, AKI. The other parameters such as days of symptoms, length of ICU stay, pre-hospitalization iRAAS use, in hospital corticosteroid use, SAPS3 and SOFA scores at hospital admission, PO2/FiO2 ratio, white cell blood counts, RCP, creatinine, bilirubin, and lactate were not statistically different between survivor groups and non-survivor groups. Clinical data are expressed as mean ± standard error of mean. BMI=Body max index, RCP=Reactive C-Protein.

Survivors (n = 30) Non-survivors (n = 23) p
Age 56.1 ± 2.2. 64.0 ± 2.4 * 0.0223
Male sex 20 (66.7%) 16 (69.6%) 0.823
Diabetes 2 (6.7%) 8 (34.8%) * 0.009
Hypertension 11 (36.6%) 18 (78.3%) * 0.006
BMI, kg/m2 29.7 ± 1 33.7 ± 2 * 0.0442
CVD 7 (23.3%) 12 (52.2%) * 0.03
iRAAS prehospitalization 13 (43.3%) 11 (47.8%) 0.744
Days of symptoms 9.7 ± 1 10.4 ± 2 0.581
Days from symptoms worsening 2.7 ± 1 3.2 ± 1 0.333
SAPS3 58.3 ± 2.1 61.2 ± 2.2 0.432
SOFA 8.2 ± 0.5 9.6 ± 0.7 0.067
Hospitalization days 17.5 ± 3 13.6 ± 2 0.692
In hospital corticoid use 26 (86.7%) 21 (91.30%) 0.597
PaO2/FiO2, ratio 138.4 ± 20 138.3 ± 19 0.996
Leukocytes 10.6 ± 0.8 10.9 + 0.95 0.805
Neutrophiles 8.4 + 0.8 9.3 + 0.91 0.459
Lymphocytes x10/ mm3 1.2 + 0.1 0.9 + 0.2 0.259
Platelets x 103/l 250 ± 150 234 ± 23 0.532
Bilirubin (mg/dL) 0.54 ± 0.1 1.14 ± 0.3 0.0547
Creatinine (mg/dL) 1.50 ± 0.2 1.65 ± 0.2 0.244
Lactate (mg/dL) 2.19 ± 0.1 2.37 ± 0.2 0.58
CRP (mg/dL) 12.55 ± 1.5 13.20 ± 1.7 0.775
AKI (mg/dL) 11(36.7%) 15(65.2%) * 0.039
Dialysis 4(13.3%) 13(56.5%) * 0.0008