Table 2.
Areas under the receiver operating characteristic curve for diagnosing Parkinson’s disease with the convolutional neural network
Metrics | Cross-validation | Pooled | ||||
---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | ||
NOS | 0.688 | 0.767 | 0.764 | 0.887 | 0.843 | 0.761 (0.698–0.823) |
DTI | ||||||
Axial diffusivity | 0.747 | 0.722 | 0.713 | 0.664 | 0.864 | 0.715 (0.649–0.781) |
Mean diffusivity | 0.726 | 0.656 | 0.713 | 0.618 | 0.783 | 0.672 (0.602–0.741) |
Radial diffusivity | 0.667 | 0.633 | 0.703 | 0.684 | 0.871 | 0.698 (0.631–0.766) |
Fractional anisotropy | 0.703 | 0.724 | 0.775 | 0.665 | 0.853 | 0.733 (0.669–0.798) |
DKI | ||||||
Axial kurtosis | 0.839 | 0.941 | 0.972 | 0.911 | 0.957 | 0.891 (0.848–0.934) |
Mean kurtosis | 0.864 | 0.845 | 0.868 | 0.860 | 0.989 | 0.878 (0.833–0.923) |
Radial kurtosis | 0.847 | 0.879 | 0.913 | 0.854 | 0.987 | 0.895 (0.853–0.937) |
NODDI | ||||||
Intracellular volume fraction | 0.784 | 0.847 | 0.798 | 0.747 | 0.896 | 0.801 (0.744–0.858) |
Isotropic volume fraction | 0.688 | 0.798 | 0.745 | 0.730 | 0.868 | 0.749 (0.686–0.811) |
Orientation dispersion | 0.561 | 0.760 | 0.743 | 0.662 | 0.817 | 0.691 (0.623–0.759) |
g-ratio | ||||||
Axon volume fraction | 0.749 | 0.871 | 0.837 | 0.926 | 0.915 | 0.836 (0.784–0.888) |
Myelin volume fraction | 0.681 | 0.773 | 0.790 | 0.788 | 0.834 | 0.763 (0.701–0.824) |
g-ratio | 0.665 | 0.760 | 0.830 | 0.786 | 0.866 | 0.767 (0.706–0.827) |
Note: The 95% confidence interval is shown in parentheses