. Author manuscript; available in PMC: 2021 Aug 20.

Published in final edited form as: Mov Disord. 2021 Apr 4;36(8):1863–1870. doi: 10.1002/mds.28575

Table 2.

Cox regression results of neuroticism predicting the risk of incident Parkinson’s disease in the entire cohort and by sex

	Full sample		Women		Men
	At-risk/PD	HR (95% CI)	PD	HR (95% CI)	PD	HR (95% CI)
Continuous	490755/1142	1.28 (1.21-1.36)	453	1.30 (1.18-1.42)	689	1.27 (1.18-1.37)
Quartile 1	122853/261	-	69	-	192	-
Quartile 2	111084/244	1.14 (0.96-1.36)	94	1.21 (0.89-1.65)	150	1.10 (0.89-1.37)
Quartile 3	134071/304	1.33 (1.13-1.58)	134	1.40 (1.05-1.88)	170	1.30 (1.06-1.60)
Quartile 4	122747/333	1.88 (1.60-2.22)	156	1.92 (1.45-2.55)	177	1.88 (1.53-2.31)

Notes: At-risk/PD refers to the number at risk and the number of incident Parkinson’s disease. Quartile 1 (lowest neuroticism score) is the reference group.