Table 2.
Association between rs4149056 genotype and statin-induced myopathy + rhabdomyolysis by statin group
Statin-type | Genotype | TT | TC | CC | MAF | χ2 p-valuea |
---|---|---|---|---|---|---|
All Statins | Cases | 153 | 64 | 16 | 0.21 | |
Controls | 1722 | 569 | 51 | 0.14 | 1.80E-06 | |
Simvastatin | Cases | 47 | 29 | 6 | 0.25 | |
Controls | 537 | 195 | 16 | 0.15 | 4.55E-04 | |
Lovastatin | Cases | 59 | 19 | 7 | 0.19 | |
Controls | 671 | 210 | 20 | 0.14 | 8.32E-04 | |
Atorvastatin | Cases | 47 | 16 | 3 | 0.17 | |
Controls | 514 | 164 | 15 | 0.14 | 0.40 |
MAF, minor allele frequency
Differences in minor allele frequency between cases and controls for each statin group.