Table 2.
Changes in tumor volume and SUVmax in ICON patients with abnormal nodes post-therapy.
| ICON cohort | |||||
|---|---|---|---|---|---|
| Pre-chemotherapy | Post-chemotherapy | Change (Post–Pre) | |||
| n | Median (min, max) | Median (min, max) | Median (min, max) | P value | |
| Tumor volume (mL) | 8* | 68.2 (2.50, 207) | 20.6 (2.60, 94.0) | −35.9 (−113, 0.10) | 0.016 |
| Tumor SUVmax | 3** | 9.30 (7.10, 19.0) | 8.90 (6.50, 9.60) | 0.30 (−14.4, 1.80) | 1.00 |
ICON ImmunogenomiC prOfiling in Non-small cell lung cancer. *Post-chemotherapy tumor volume was not measurable (atelectasis) in one patient. **Six patients did not have paired tumor SUVmax values. SUVmax, maximum standardized uptake value. Two-sided P value is from Wilcoxon signed-rank test for paired tumor volume and tumor SUVmax comparisons. Source data are provided as a Source Data file.