A, B About 840-nm Retina Depth Encoded OCTA in patient eyes showed blood vessels in the CM with predominantly heterogeneously distributed and disorganised intratumoural vasculature. There was good penetration of flow signal in the CM in OCTA. The vascular and perfusion density within CM were measured from AngioPlex MetrixTM OCTA images. C, D The vascular and perfusion density in CM and macular areas were measured from AngioPlex MetrixTM OCTA images. Nine main regions were evaluated for the purposes of this study (6 × 6 mm). C Vascular density (VD), D perfusion density (PD). E, F After radiation treatment, OCTA that showed the progressive reduction in tumour vessel density over time was observed in choroidal melanomas treated with radioactive plaques. E Pre-PRT. F Aft-PRT.