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. 2021 Aug 19;11:16821. doi: 10.1038/s41598-021-96256-0

Table 3.

Significantly enriched pathways.

Gene ontologies GO term q-value Dispensability
BP GO:0006491N-glycan processing 0.042 0
BP GO:0016064 immunoglobulin mediated immune response 7.23 × 10–4 0
BP GO:0006959 humoral immune response 0.036 0.692
BP GO:0042129 regulation of T cell proliferation 0.035 0.637
BP GO:0002377 immunoglobulin production 3.69 × 10–3 0.632
BP GO:0002889 regulation of immunoglobulin mediated immune response 0.040 0.947
BP GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response 0.035 0.952
BP GO:0034112 positive regulation of homotypic cell–cell adhesion 0.036 0.722
BP GO:0019724 B cell mediated immunity 1.42 × 10–3 0.924
BP GO:0002712 regulation of B cell mediated immunity 0.040 0.947
BP GO:0002440 production of molecular mediator of immune response 5.25 × 10–3 0.627
BP GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.043 0.933
BP GO:0002637 regulation of immunoglobulin production 0.049 0.888
BP GO:1903039 positive regulation of leukocyte cell–cell adhesion 0.040 0.979
BP GO:0002455 humoral immune response mediated by circulating immunoglobulin 0.035 0.952
BP GO:0050870 positive regulation of T cell activation 0.039 0.933
CC GO:0042613 MHC class II protein complex 1.83 × 10–5 0
CC GO:0042611 MHC protein complex 3.21 × 10–3 0.501
CC GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane 4.37 × 10–3 0.032
CC GO:0098576 lumenal side of membrane 0.035 0.513
CC GO:0098553 lumenal side of endoplasmic reticulum membrane 4.37 × 103 0.606
MF GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 6.87 × 10–3 0
MF GO:0030983 mismatched DNA binding 1.42 × 10–3 0
MF GO:0032395 MHC class II receptor activity 8.59 × 10–5 0
MF GO:0005542 folic acid binding 0.036 0.066
MF GO:0017091 AU-rich element binding 0.040 0.149
MF GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 0.035 0.299

Gene Ontologies: Molecular Function (MF), Biological Process (BP), Cellular Component (CC). Dispensability represents a measure of the non-redundancy of a GO term with respect to other semantically close terms. Representative, non-redundant GO terms are given in black, the other cluster members are in italics.