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. 2021 Aug 19;7:217. doi: 10.1038/s41420-021-00585-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — A, B The expression of PSMC2 and ITGA6 in SK-HEP-1 cells transfected with shCtrl, shITGA6 and simultaneous shPSMC2 and shITGA6 were detected by qPCR (A) and western blotting (B). Cell models were adopted in the detection of cell proliferation by Celigo cell counting assay (C), colony formation (D), cell apoptosis (E), and cell migration by wound-healing assay (F) and Transwell assay (G). The representative images were selected from at least three independent experiments. Data were shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.