Table 3.
Predictive validity of sarcopenia indices on overall mortality, overall and stratified by gender.
| AUC (95% CI) | Cut-off | Sen (%) | Spe (%) | PPV (%) | NPV (%) | |
|---|---|---|---|---|---|---|
| Low Cr/CysC | ||||||
| Overall | 0.647 (0.619–0.675)* | |||||
| Male | 0.665 (0.628–0.701)* | 0.98 | 65.2 | 64.4 | 17.5 | 94.1 |
| Female | 0.638 (0.593–0.681)* | 0.88 | 72.3 | 55.1 | 15.0 | 94.8 |
| Low eGFRcys/eGFRcre | ||||||
| Overall | 0.702 (0.674–0.728)* | |||||
| Male | 0.714 (0.678–0.748)* | 0.83 | 65.2 | 71.3 | 20.8 | 94.6 |
| Female | 0.688 (0.644–0.729)* | 1.01 | 87.2 | 47.4 | 15.4 | 97.1 |
| Low eGFRDiff | ||||||
| Overall | 0.646 (0.618–0.674)* | |||||
| Male | 0.659 (0.622–0.695)* | − 4.2 | 73.9 | 57.7 | 16.8 | 95.0 |
| Female | 0.632 (0.587–0.675)* | − 0.6 | 87.2 | 42.6 | 14.2 | 96.8 |
| Low Cr × eGFRcys | ||||||
| Overall | 0.728 (0.701–0.753)* | |||||
| Male | 0.758 (0.723–0.790)* | 56.3 | 78.3 | 66.9 | 21.5 | 96.4 |
| Female | 0.732 (0.690–0.771)* | 48.3 | 85.1 | 54.7 | 17.0 | 97.1 |
AUC area under curves, CI confidence interval, Sen sensitivity, Spe specificity, PPV positive predictive value, NPV negative predictive value.
*p < 0.05 was considered statistically significant.