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. 2021 Aug 6;12:705126. doi: 10.3389/fneur.2021.705126

Table 3.

FGID according to demographic and clinical characteristics of the population.

Total FGID+ (75) FGID- (45) p value
120 N (%) N (%)
Sex
Male 58 33 (56.9) 25 (43.1) n.s.
Female 62 42 (67.7) 20 (32.3)
Age of onset
>10 years 83 54 (65.1) 29 (34.9) n.s.
<10 years 37 21 (56.8) 16 (43.2)
Disease duration
<10 years 25 18 (72.0) 7 (28.0) n.s.
>10 years 95 57 (60.0) 38 (40.0)
Epilepsy syndrome
Focal 85 53 (62.4) 32 (37.6) n.s.
Epileptic encephalopathy 3 2 (66.7) 1 (33.3)
Idiopathic generalized 32 20 (62.5) 12 (37.5)
Etiology of focal epilepsies
Symptomatic 42 24 (57.1) 18 (42.9) n.s.
Unknown/idiopathic 43 26 (60.5) 17 (39.5)
Response to therapy
Responsive 49 29 (61.2) 20 (38.8) n.s.
Drug-resistant 71 46 (63.4) 25 (36.6)
Therapy regimen
Polytherapy 81 53 (65.4) 28 (34.6) n.s.
Monotherapy 37 20 (54.1) 17 (45.9)
None 2 2 (100) 0 (0.0)
ASM generation
First generation 85 48 (56.5) 37 (43.5) n.s.
Second/third generation 33 25 (75.8) 8 (24.2)
Seizure rate in drug-resistant epilepsy
Annual/monthly 34 23 (67.6) 11 (32.4) n.s.
Weekly/daily 37 23 (62.2) 14 (37.8)
Lobar involvement in focal epilepsy
Temporal 39 30 (76.9) 9 (23.1) 0.02
Extra-temporal 46 23 (50.0) 23 (50.0)

ASM, antiseizure medication; FGID, functional gastrointestinal disorder.