Skip to main content
. 2021 Aug 6;12:692165. doi: 10.3389/fimmu.2021.692165

Figure 2.

Figure 2

Innate immune primary response of human monocytes to NP alone or upon co-exposure with LPS. Human monocytes isolated from blood of four individual donors (red, green, blue, and yellow symbols) were cultured for 24 h in culture medium alone (empty columns) or containing serum-precoated NP: 5.7 µg/ml spherical AuNP (AuNP SPH), 1.4 µg/ml rod-shaped AuNP (AuNP ROD), 2 µg/ml spherical FeOxNP of 16.8 nm diameter (FeOxNP 17) and 2.7 µg/ml spherical FeOxNP of 22.4 nm diameter (FeOxNP 22) alone (light blue columns) or together with 1 ng/ml LPS (orange columns). The production of TNFα (upper left), IL-6 (upper right), IL-10 (lower left) and IL-1Ra (lower right) was measured in the 24 h supernatants by ELISA. Data are presented as individual donors’ values (coloured symbols) ± SD and as mean of the individual values (dotted columns).