Table 2.
NP hydrodynamic features.
| Parameter | AuNP SPH | AuNP ROD | FeOxNP 17 | FeOxNP 22 |
|---|---|---|---|---|
| Dv (nm)a | 16 ± 2 (WFI)b | 17 ± 4 (WFI) | 20 ± 1 (WFI) | 21 ± 3 (WFI) |
| 17 ± 7 (PBS 1x) | 22 ± 4 (PBS 1x) | NA | NA | |
| 100 ± 20 (RPMI) | 120-170 (RPMI) | 18 ± 2 (RPMI)d | 17 ± 5 (RPMI)d | |
| 38 ± 2 (RPMI)c | 22 ± 2 (RPMI)c | NA | NA | |
| ζ-potential (mV)e | −53 ± 2 | −39 ± 4 | −18 ± 2 | −29 ± 3 |
| Endotoxin activity | 0.45 EU/mg | 30.8 EU/mg | 58.3 EU/mg | <16 EU/mg |
a
Volume-weighted hydrodynamic diameter; for Au nanorods, it is the volume-weighted hydrodynamic diameter of spherical NP having the same average diffusion coefficient of the nanorods.
b
WFI, water for injection.
c
NP were pre-treated with 50% human serum.
d
RPMI plus 5% FBS.
e
in PBS 1x.
NA, not available.