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. 2021 Aug 6;8:683900. doi: 10.3389/fmed.2021.683900

Table 2.

Comparison of onychoscopic features between connective tissue diseases and healthy controls.

Onychoscopic features SLE ( N = 54) DM ( N = 32) SSc ( N = 51) p -Value (among CTDs) Controls ( N = 108) p -Value (CTDs vs. controls)
Tortous capillaries N (%) 48 (88.8%) 31 (96.8%) 50 (98%) 0.125 96 (88.8%) 0.125
Bushy capillaries N (%) 27 (50%) 21 (65.6%) 10 (19.6%) <0.001* 4 (3.7%) <0.001*
Elongated capillaries N (%) 12 (22.2%) 3 (9.3%) 4 (7.8%) 0.073 4 (3.7%) 0.003*
Subpapillary plexus N (%) 28 (51.8%) 9 (28.1%) 8 (15.6%) <0.001* 15 (13.8%) <0.001*
Hemorrhage N (%) 10 (18.5%) 11 (34.4%) 26 (50.9%) 0.002* 3 (2.7%) <0.001*
Enlarged capillaries N (%) 25 (46.2%) 21 (65.6%) 38 (74.5%) 0.01* 27 (25%) <0.001*
Disorganized capillaries N (%) 43 (79.6%) 31 (96.8%) 46 (90.1%) 0.05 21 (19.4%) <0.001*
Avascular areas N (%) 41 (75.9%) 30 (93.7%) 49 (96%) 0.004* 10 (9.2%) <0.001*
Density (mean ± SD) 6.83 ± 1.95 5.31 ± 1.86 5.09 ± 1.69 0.592 7.43 ± 1.20 <0.001*

CTDs, connective tissue diseases; DM, dermatomyositis; SD, standard deviation; SLE, systemic lupus erythematosus; SSc, systemic sclerosis.

*

Statistically significant.