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. 2021 Aug 6;13:718959. doi: 10.3389/fnagi.2021.718959

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Copyright © 2021 Lin, Xue, Li, Chen, Tao and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prevalence of different AT(N) categories in different AT(N) variants among cognitively unimpaired (CU) (A) and cognitively impaired (CI) (B) participants in the ADNI. CSF Aβ42 (A1); amyloid PET whole cerebellum standardized uptake value ratio (SUVR) (A2); CSF tau phosphorylated at Thr181 (T1); tau PET inferior temporal cortex SUVR (T2); tau PET Braak V/VI SUVR (T3); hippocampal volume [(N)1]; temporal meta-ROI thickness [(N)2]; CSF total tau [(N)3]; FDG PET meta-ROI SUVR [(N)4]; plasma neurofilament light [(N)5]. AT(N), β-amyloid, tau, and neurodegeneration classification system.