Supplementary figure S7.

Heterogeneous regulator subpopulations within a single isolate. The symbols and question marks in the figure indicate the following questions from left to right. Under an optimal growth condition, do alternative regulators transcribe/translate genes? Does sigma factor regulate the expression of functionally specialized ribosomal rRNA and protein coding genes? Do heterogeneous regulator subpopulations produce structurally different gene products? Under environmental stress, do major regulators transcribe/translate genes?