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. 2021 Jul-Sep;13(3):116–122. doi: 10.18502/ajmb.v13i3.6371

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Copyright© 2021 Avicenna Research Institute

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Figure 2. — Up) the impact of Nrf2 inhibition by Brusatol (Bru) and Luteolin (Lut) and activation by tBHQ on Nrf2 and PD-L1 mRNA expression levels. The sensitive and resistant (Res) SW480 colon cancer cells were treated with Brusatol (40 nM) and Luteolin (20 μM) alone or in combination and tert-buthylhydroquinone (20 μM) for 24 hr. The results were gathered at least from three independent experiments and finally expressed as mean±SD. *** p<0.001. Down) the impact of Nrf2 inhibition by Brusatol (Bru) and Luteolin (Lut) and activation by tBHQ on Nrf2 and PD-L1 mRNA expression levels. The sensitive and resistant (Res) LS174T colon cancer cells were treated with Brusatol (40 nM) and Luteolin (20 μM) alone or in combination and tert-buthylhydroquinone (20 μM) for 24 hr. The results were gathered at least from three independent experiments and finally expressed as mean±SD. *** p<0.001.