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. 2021 Jul-Sep;13(3):116–122. doi: 10.18502/ajmb.v13i3.6371

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Copyright© 2021 Avicenna Research Institute

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Figure 4. — A) the impact of Nrf2 siRNA on oxaliplatin-induced apoptosis in resistant SW480 colon cancer cells. SW480 resistant colon cancer cells were transfected with Nrf2 siRNA (Nrf2 si) (80 pmol) which was also followed by oxaliplatin (Oxp) (89/60 μM) for 48 hr. B) the impact of Nrf2 siRNA on reduction of migration in resistant SW480 colon cancer cells. SW480 resistant colon cancer cells were transfected with Nrf2 siRNA (Nrf2 si) (80 pmol) which was also followed by oxaliplatin (Oxp) (89/60 μM) for 48 hr. Then, the cells’ motility was monitored by wound-healing assay for 0, 24, and 48 hr. The results were gathered at least from three independent experiments and finally expressed as mean±SD. * p<0.05.