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. 2021 Aug 20;21:169. doi: 10.1186/s12902-021-00824-4

Table 3.

Changes in the number of masses in all participants and in single and multiple fibroadenomas

Metformin Group Placebo Group   p-value
Single mass-total; n (%) 39 (100) 56 (100) 0.74
  Disappearance 4 (10.2) 7 (12.5)
  Without change 34 (87.2) 46 (82.1)
  Increased number 1 (2.6) 3 (5.4)
Multiple mass-total; n (%) 44 (100) 36 (100) 0.08
  Disappearance 6 (13.6) 3 (8.3)
  Without change or decreased  34 (77.3) 23 (63.9)
  Increased number 4 (9.1) 10 (27.8)
In all cases; n (%) 83 (100) 92 (100) 0.21
  Disappearance 10 (12.1) 10 (10.9)
  Without change or decreased  68 (81.9) 69 (75)
  Increased number 5 (6) 13 (14.1)

P-value refers to Chi-square test.