Table 4. Association of Body Size, Body Fat Distribution, and Body Composition With All-Cause Mortality by Age Among Black Breast Cancer Survivorsa.
| Variable | Age ≤45 y | Age 46-59 y | Age ≥60 y | P value for interaction |
|---|---|---|---|---|
| Baseline BMI | ||||
| Participants, No. | 415 | 878 | 596 | .91 |
| Total deaths | 68 | 121 | 97 | |
| HR (95% CI) per 5.0 U | 1.22 (1.01-1.49) | 1.06 (0.94-1.19) | 1.14 (0.99-1.31) | NA |
| Waist circumference, cm | ||||
| Participants, No. | 409 | 868 | 580 | .16 |
| Total deaths | 66 | 118 | 90 | |
| HR (95% CI) per 10.0 cm | 1.16 (0.97-1.40) | 1.07 (0.96-1.19) | 1.28 (1.12-1.46) | NA |
| Waist-to-hip ratio | ||||
| Participants, No. | 409 | 868 | 580 | .01 |
| Total deaths | 66 | 118 | 90 | |
| HR (95% CI) per 0.10 U | 0.90 (0.65-1.25) | 1.25 (0.97-1.60) | 1.76 (1.37-2.26) | NA |
| Body fat, % | ||||
| Participants, No. | 397 | 825 | 543 | .21 |
| Total deaths | 63 | 108 | 86 | |
| HR (95% CI) per 5.0 U | 1.13 (0.93-1.37) | 1.01 (0.89-1.14) | 1.20 (1.00-1.40) | NA |
| FMI | ||||
| Participants, No. | 397 | 826 | 541 | .56 |
| Total deaths | 63 | 109 | 86 | |
| HR (95% CI) per 5.0 U | 1.35 (1.0-1.80) | 1.06 (0.89-1.26) | 1.26 (1.02-1.57) | NA |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); FMI, fat mass index (calculated as fat mass in kilograms divided by height in meters squared); HR, hazard ratio; NA, not applicable.
a
Hazard ratios and 95% CIs were adjusted for age, income, smoking status, tumor stage, tumor subtype, and type of surgery.