Table 1.
Patient demographic, admission, technical, radiographic, and clinical outcome variables
| Variable | AF |
No AF |
Test | Standardized mean difference | P value | ||
|---|---|---|---|---|---|---|---|
| N | Mean (SD) Median (IQR) N (%) |
N | Mean (SD) Median (IQR) N (%) |
||||
| Demographics | |||||||
| Age | 1517 | 76 (11) | 2652 | 65 (15) | t-test | 0.75 | 0.001 |
| Female | 1517 | 877 (58%) | 2651 | 1299 (49%) | Chi-sq | 0.02 | |
| White race | 1133 | 754 (67%) | 2107 | 1241 (59%) | Chi-sq | 0.001 | |
| Comorbidities | |||||||
| Diabetes | 1511 | 453 (30%) | 2650 | 721 (27%) | Chi-sq | 0.06 | |
| Hypertension | 1517 | 1252 (83%) | 2652 | 1860 (70%) | Chi-sq | 0.001 | |
| Hyperlipidemia | 1514 | 668 (44%) | 2652 | 979 (37%) | Chi-sq | 0.001 | |
| Prior stroke | 1070 | 196 (18%) | 1982 | 287 (14%) | Chi-sq | 0.006 | |
| Pre-stroke mRS score 0–2 | 1085 | 986 (91%) | 2022 | 1871 (93%) | Chi-sq | 0.121 | |
| Admission variables | |||||||
| Admission NIHSS score | 1502 | 16 (6) | 2630 | 15 (7) | t-test | 0.15 | 0.001 |
| ASPECTS | 1112 | 8 (2) | 1889 | 9 (3) | MW | 0.37 | 0.015 |
| IV tPA use | 1401 | 651 (46%) | 2498 | 1340 (54%) | Chi-sq | 0.001 | |
| Onset-to-groin time (hours) | 1139 | 5.9 (7.2) | 2147 | 6.1 (8.4) | t-test | 0.02 | 0.476 |
| Procedural variables | |||||||
| Procedure time (min) | 1331 | 51 (43) | 2382 | 56 (44) | t-test | 0.10 | 0.002 |
| Total attempts | 1368 | 2.1 (1.6) | 2439 | 2.3 (1.7) | MW | 0.12 | 0.001 |
| First pass success | 902 | 377 (42%) | 1574 | 552 (35%) | Chi-sq | 0.001 | |
| Final TICI score | 1437 | 2477 | Chi-sq | 0.301 | |||
| 0–2a | 233 (16%) | 369 (15%) | |||||
| 2b–3 | 1204 (84%) | 2108 (85%) | |||||
| ICA angioplasty | 1437 | 0 (0.0%) | 1481 | 82 (6%) | Chi-sq | 0.001 | |
| Complications | 909 | 78 (9%) | 1841 | 157 (9%) | Chi-sq | 0.999 | |
| Hemorrhage (any type) | 1322 | 300 (23%) | 2382 | 571 (24%) | Chi-sq | 0.396 | |
| Hemorrhage (PH2/sICH) | 1165 | 89 (8%) | 2197 | 160 (7%) | Chi-sq | 0.729 | |
| Outcome | |||||||
| mRS score: discharge | 796 | 4 (3) | 1319 | 3 (3) | MW | 0.12 | 0.001 |
| mRS score: 90 days | 1368 | 4 (2) | 2439 | 3 (3) | MW | 0.30 | 0.001 |
| mRS score 0–2 | 1368 | 426 (31%) | 2434 | 1029 (42%) | Chi-sq | 0.001 | |
| mRS score 3–6 | 1368 | 942 (69%) | 2434 | 1405 (58%) | Chi-sq | 0.001 | |
| Mortality: 90 days | 1368 | 354 (26%) | 2434 | 408 (17%) | Chi-sq | 0.001 | |
Statistical tests were done using t-tests, chi squared tests (Chi-sq), or Mann-Whitney (MW) tests. A standardized mean difference >0.10 is considered meaningful.
AF, atrial fibrillation; ASPECTS, Alberta Stroke Program Early CT Score; ICA, internal carotid artery; IV tPA, intravenous tissue plasminogen activator; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; PH2, parenchymal hematoma type II (ECASS II criteria); sICH, symptomatic intracranial hemorrhage; TICI, thrombolysis in cerebral infarction.