TABLE 1.
Active phase |
Inactive phase |
||||
---|---|---|---|---|---|
Group | Meters run | Max speed | Meters run | Max speed | Figure |
| |||||
Sham + saline | 83,947 (6,552) | 3,586 (30) | 2,285 (687) | 26 (7) | 1 |
CCI + saline | 56,745 (2,497)** | 244 (14)** | 3,352 (579) | 42 (5) | 1 |
CCI + morphine + saline | 54,747 (2,769) | 249 (16) | 2,753 (618) | 25 (5) | 2, S2 |
CCI + morphine + (+)-NLX | 85,577 (7,015)### | 406 (29)# | 3,290 (822) | 44 (11) | 2, S2 |
CCI + morphine + A438079 | 74,045 (4,609)### | 348 (25)# | 3,341 (555) | 51 (10) | 2, S2 |
CCI + saline + saline | 53,655 (2,470) | 190 (12) | 4,203 (617) | 47 (5) | 2, S4 |
CCI + saline + (+)-NLX | 58,583 (3,297) | 228 (21) | 2,766 (554) | 26 (5) | 2, S4 |
CCI + saline + A438079 | 49,544 (4,067) | 181 (18) | 3,508 (565) | 33 (5) | 2, S4 |
Sham + morphine + saline | 82,317 (6,256) | 392 (28) | 4,919 (832) | 53 (9) | 3, S5 |
Sham + morphine + (+)-NLX | 89,742 (8,101) | 433 (33) | 4,952 (1,056) | 71.08 (16) | 3, S5 |
Sham + morphine + A438079 | 101,727 (7,561) | 421 (28) | 4,117 (726) | 34 (7) | 3, S5 |
Sham + saline | 62,152 (5,834) | 260 (25) | 2,124 (682) | 24 (6) | 4 |
Sham + morphine | 82,317 (6,256)$ | 392 (28)$$ | 2,815 (645) | 39 (8) | 4 |
Note: Relative to Sham + saline:
p < 0.01;Relative to CCI + morphine + saline:
p < 0.05,
p < 0.001; Relative to Sham + saline:
p < 0.05,
p < 0.01.