Table 1.
Overall demographics
| rTOF patients (n = 58) | RV dilation patients (n = 28) | p | Normal controls (n = 12) | p | |
|---|---|---|---|---|---|
| Demographics | |||||
| Age (years), IQR | 21.7 (12.2–29.6) | 11.5 (4.0–15.5) | < 0.001 | 13.9 (9.1–17.7) | 0.038 |
| Female | 30 (51%) | 14 (50%) | 6 (50%) | ||
| BSA (m2) | 1.5 ± 0.40 | 1.2 ± 0.6 | < 0.001 | 1.4 ± 0.5 | ns |
| Native anatomy | |||||
|
TOF-PS 47 (84%) TOF-PA 11 (16%) |
PAPVR 24 (85%) 2° ASD 4 (15%) |
||||
| CMR data | |||||
| RVEDV (mL) | 203 ± 81 | 165 ± 110 | ns | 131 ± 55 | 0.0017 |
| RVEDVI (mL/m2) | 131 ± 33 | 148 ± 57 | ns | 86 ± 15 | < 0.001 |
| RVESVI (mL/m2) | 65 ± 21 | 61 ± 29 | ns | 38 ± 10 | < 0.001 |
| RVEF (%) | 51.1% ± 5.5% | 60.4% ± 6.1% | < 0.001 | 60.0% ± 5.8% | < 0.001 |
| PR% | 27.9% ± 16.4% | 0.0 ± 0.04% | < 0.001 | 0.0 ± 0.03% | < 0.001 |
| Qp:Qs | 1.0 ± 0.05 | 2.5 ± 1.4 | < 0.001 | 1.0 ± 0.08 | ns |
Fifty-eight repaired tetralogy of Fallot (rTOF) patients, 28 patients with right ventricular (RV) dilation and twelve normal controls were included. RV dilation patients had either partial anomalous pulmonary venous return (PAPVR) or large secundum type atrial septal defects (2° ASD). There was selection bias in that rTOF patients tended to be older and larger than RV dilation patients, although had similar indexed right ventricular end-diastolic volume index (RVEDVI) and RV end-systolic volume index (RVESVI)
BSA body surface area, RVEF right ventricular ejection fraction, PR% pulmonary regurgitation percent