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. 2021 Aug 19;27:92. doi: 10.1186/s10020-021-00351-x

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — H₂O₂ induces high levels of oxidative stress in NPCs. A RT-qPCR results of the oxidative stress factors iNOS, SOD2 and NOX4 (*p < 0.05). B RT-qPCR results of the inflammatory cytokines IL-1β, IL-6, and TNF-α (*p < 0.05). C Western blot results for iNOS, SOD2, and NOX4. D Western blot results for IL-1β, IL-6, and TNF-α. E Quantitative analysis of Western blot for iNOS, SOD2, NOX4 (*p < 0.05). F Quantitative analysis of Western blot for IL-1β, IL-6, TNF- α (*p < 0.05). (n = 3 Independent experiments)