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. 2021 Aug 20;23:218. doi: 10.1186/s13075-021-02588-7

Fig. 3.

Fig. 3

Synovial fluid concentrations of A TNF-α, B IL-1β, C CCL2, D CCL3, E CCL5, and F CCL11 were measured using a multiplex assay (n = 20 healthy and n = 54 OA joints). TNF-α was increased in OA joints, and CCL11 was decreased in OA joints. CCL2 and CCL5 did not differ between healthy and OA joints. ns, not significant; *P < 0.05, **P < 0.01. Data are displayed as box-and-whisker plots representing the first and third quartiles, median, and spread of concentrations for healthy and OA samples