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. 2021 Aug 19;9:140. doi: 10.1186/s40478-021-01239-x

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Gene ontology and molecular pathway analyses of transcriptomic changes in recovery-phase microglia. A Statistical significance of overrepresented gene ontology annotations (biological pathway subcategory) among genes showing significantly higher expression (log₂ fold change > 1, Benjamini–Hochberg adjusted P-value < 0.05) in recovery-phase relative to control microglia in the cortex (left panel) or spinal cord (right panel). B Statistical significance of overrepresented Reactome pathway annotations among genes showing significantly higher expression (log₂ fold change > 1, Benjamini–Hochberg adjusted P-value < 0.05) in recovery-phase relative to control microglia in the cortex (left panel) or spinal cord (right panel)